Chronic Myeloid Leukemia-CML
Chronic Myeloid Leukemia (CML) is a blood cancer caused by genetic changes in bone marrow cells, leading to uncontrolled growth of myeloid cells.
The disease often progresses slowly but can eventually transform into an aggressive phase if untreated. Modern therapies, including tyrosine kinase inhibitors (TKIs), have significantly improved survival and quality of life for patients with CML.
Causes and Risk Factors of CML
CML results from a genetic abnormality called the Philadelphia chromosome, which produces a protein promoting uncontrolled cell growth.
- Age factor: Most commonly diagnosed in adults between 40 and 60 years old.
- Exposure to high doses of radiation may slightly increase risk.
- No direct lifestyle cause, but family history may influence susceptibility.
Symptoms and Early Detection
CML may remain asymptomatic for months or years. When present, symptoms include fatigue, night sweats, unexplained weight loss, and mild fever.
- Enlarged spleen causing abdominal fullness
- Easy bruising or bleeding
- Frequent infections: Due to compromised immune system
Treatment Approaches for CML
Modern treatments aim to control cell growth and prevent disease progression.
- Tyrosine kinase inhibitors: Targeted drugs that block the protein produced by the Philadelphia chromosome.
- Stem cell transplantation: Considered for resistant or advanced cases.
- Supportive care includes blood count monitoring and symptom management.
Why Choose Us for CML
CureU Healthcare provides cutting-edge therapies, expert monitoring, and personalized care to manage CML effectively and safely.
Conclusion
CML is a manageable blood cancer with timely treatment. CureU Healthcare ensures optimal therapy and close follow-up for the best outcomes.
